During my secondment at the Yusuf Hamid Department of Chemistry at Cambridge University from 1 – 16 July, I had the pleasure of working closely with Prof. Michele Vendruscolo, where I was introduced to computational methods for the in-silico design and mutation of the Fc region of antibodies and predicting the outcome in terms of affecting the stability of the Fc region and the binding affinity towards different Fc receptors. I was very excited to learn computational biology techniques, so I would very much like to thank Prof. Michele Vendruscolo for taking the time to introduce me to new tools and guide me through the process. I would also like to extend my thanks to my fellow ESRs at Cambridge University, Vaidehi Roy Chowdhury and Alexander Roentgen. Cambridge is such a historical city with a rich culture that I was happy to explore.
by Lisa Wünsche