The overall goal of this subproject is the development of a Safe-by-Design data-based computational platform for the intranasal drug delivery system in support of toxicological determination of intranasal drug delivery systems.

The specific goals are :

  1. Safe-by-Design approach by means of data-based modelling);
  2. Optimal design of Drug Delivery Systems, based on innovative safe-by-design computational tools and methodology.

This subject will be divided in two parts:

  • 3D-Bioprinting mimetics for nose to brain drug delivery.
  • Use of Artificial intelligence Tools to identify critical parameters for drug administration.
  • Design optimization