The overall goal of this subproject is the development of a Safe-by-Design data-based computational platform for the intranasal drug delivery system in support of toxicological determination of intranasal drug delivery systems.
The specific goals are :
- Safe-by-Design approach by means of data-based modelling);
- Optimal design of Drug Delivery Systems, based on innovative safe-by-design computational tools and methodology.
This subject will be divided in two parts:
- 3D-Bioprinting mimetics for nose to brain drug delivery.
- Use of Artificial intelligence Tools to identify critical parameters for drug administration.
- Design optimization